Early Adverse Events, HPA Activity and Rostral Anterior Cingulate Volume in MDD

EARLY ADVERSE EVENTS, HPA ACTIVITY AND ANTERIOR CINGULATE VOLUME IN MAJOR DEPRESSIVE DISORDER By

Inferior Frontal and Cingulate Volume as Markers of Poor Outcome in Depression Brain morphometry changes in MDD over 2 years

Early prediction of recurrence of depressive episodes in major depressive disorder (MDD) is key for prevention and decreasing disease burden. We investigated 1) the predictive value of regional brain volume abnormalities (anterior and posterior cingulate, inferior frontal gyrus, and hippocampus) for recurrence or recovery over a 2-year interval; and 2) whether structural changes progressed with...

P152: Functional and Structural Brain Changes across Childhood Traumatic Events

Although childhood is connected with high neuroplasticity changes, but because of the immaturity of the neural and cognitive systems, it is ready to grow developmental deviations and future susceptibility for neuropsychological disorders. Young children face cognitive, emotional, and linguistic limits that may lead them more vulnerable to post-traumatic stress disorder (PTSD). PTSD prevalence d...

Limbic over-activity in depression during preserved performance on the n-back task.

The profile of cognitive dysfunction observed in patients with major depressive disorder (MDD) may be partially attributed to a deficit in the central executive component of working memory (WM). This could be the consequence of a functional deficit in regions of cortex that are associated with WM function in healthy adults. In order to investigate this assertion, ten patients with a diagnosis o...

A meta-analysis of neurofunctional imaging studies of emotion and cognition in major depression

Major depressive disorder (MDD) is characterized by altered emotional and cognitive functioning. We performed a voxel-based whole-brain meta-analysis of functional neuroimaging data on altered emotion and cognition in MDD. Forty peer-reviewed studies in English-language published between 1998 and 2010 were included, which used functional neuroimaging during cognitive-emotional challenge in adul...